Jump to main content
Jump to site search

Issue 24, 2018
Previous Article Next Article

Preparation and characterization of a novel silica–KF composite and facile fluorination of aromatic substrates

Author affiliations

Abstract

A novel silica–KF reagent prepared by hydrolyzing tetraethyl orthosilicate in the presence of KF for fluorination of activated aromatic compounds has been reported. The reagent, as characterized by techniques such as SEM-EDX, XRD and IR spectroscopy, is shown to have potassium cations entrapped inside the silica matrix whereas fluoride anions remain on the surface. Reaction of activated chlorinated aromatic substrates with this silica–KF leads to formation of Meisenheimer complex, either in situ or isolable, finally resulting in regioselective fluorinated aromatics.

Graphical abstract: Preparation and characterization of a novel silica–KF composite and facile fluorination of aromatic substrates

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Jul 2018, accepted on 08 Nov 2018 and first published on 10 Nov 2018


Article type: Paper
DOI: 10.1039/C8NJ03559H
Citation: New J. Chem., 2018,42, 20095-20100

  •   Request permissions

    Preparation and characterization of a novel silica–KF composite and facile fluorination of aromatic substrates

    S. S. Patel, M. D. Bochare and M. S. Degani, New J. Chem., 2018, 42, 20095
    DOI: 10.1039/C8NJ03559H

Search articles by author

Spotlight

Advertisements