Jump to main content
Jump to site search

Issue 22, 2018
Previous Article Next Article

Enhanced peroxidase-like activity of porphyrin functionalized ZnFe2O4 hollow nanospheres for rapid detection of H2O2 and glucose

Author affiliations

Abstract

Using a simple one-pot solvothermal method, binary metal oxide, magnetic and hollow ZnFe2O4 nanospheres functionalized with 5,10,15,20-tetrakis(4-carboxylphenyl)-porphyrin (Por–ZnFe2O4 HSs) were prepared and subsequently applied as a substitute for natural peroxidase. The Por–ZnFe2O4 HSs were characterized using powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). In comparison with bare ZnFe2O4 HSs, Por–ZnFe2O4 HSs exhibit enhanced intrinsic peroxidase-like activity. They demonstrate a fast colorimetric response to H2O2 with a detection limit as low as 0.86 μM. The catalytic mechanism of the system was proved to be a hydroxyl radical mechanism using electron spin resonance (ESR). By combining the Por–ZnFe2O4 HSs-catalyzed reaction and the enzymatic oxidation of glucose with glucose oxidase, a colorimetric platform for glucose detection was established. The Por–ZnFe2O4 HSs/glucose oxidase (GOx)/TMB system shows a good response toward glucose with a detection limit of 5.5 μM. Therefore, such nanocomposites have promising applications in biomimetic catalysis and environmental monitoring.

Graphical abstract: Enhanced peroxidase-like activity of porphyrin functionalized ZnFe2O4 hollow nanospheres for rapid detection of H2O2 and glucose

Back to tab navigation

Supplementary files

Publication details

The article was received on 12 Feb 2018, accepted on 04 Oct 2018 and first published on 05 Oct 2018


Article type: Paper
DOI: 10.1039/C8NJ00720A
Citation: New J. Chem., 2018,42, 18189-18200
  •   Request permissions

    Enhanced peroxidase-like activity of porphyrin functionalized ZnFe2O4 hollow nanospheres for rapid detection of H2O2 and glucose

    B. Bian, Q. Liu and S. Yu, New J. Chem., 2018, 42, 18189
    DOI: 10.1039/C8NJ00720A

Search articles by author

Spotlight

Advertisements