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Omics approaches for subcellular translation studies

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Abstract

Compartmentalized translation allows rapid synthesis of proteins in targeted cellular locations. Microarray and RNA sequencing combined with physical subcellular separation methods have enabled extensive charting of subcellular transcriptomes. However, the extent of translating these local messages into protein remains relatively understudied at the genome-wide level. Here we review omics methods currently available for these studies, placing special attention on methods allowing cell-specific and subcellularly restricted analysis.

Graphical abstract: Omics approaches for subcellular translation studies

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Publication details

The article was received on 26 Jul 2018, accepted on 10 Oct 2018 and first published on 10 Oct 2018


Article type: Review Article
DOI: 10.1039/C8MO00172C
Citation: Mol. Omics, 2018, Advance Article
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    Omics approaches for subcellular translation studies

    I. Koppel and M. Fainzilber, Mol. Omics, 2018, Advance Article , DOI: 10.1039/C8MO00172C

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