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Omics Approaches for Subcellular Translation Studies

Abstract

Compartmentalized translation allows rapid synthesis of proteins in targeted cellular locations. Microarray and RNA sequencing combined with physical subcellular separation methods have enabled extensive charting of subcellular transcriptomes. However, the extent of translating these local messages into protein at the genome-wide level remains relatively understudied. Here we review omics methods currently available for these studies, placing special attention on methods allowing cell-specific and subcellularly restricted analysis.

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Publication details

The article was received on 26 Jul 2018, accepted on 10 Oct 2018 and first published on 10 Oct 2018


Article type: Review Article
DOI: 10.1039/C8MO00172C
Citation: Mol. Omics, 2018, Accepted Manuscript
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    Omics Approaches for Subcellular Translation Studies

    I. Koppel and M. Fainzilber, Mol. Omics, 2018, Accepted Manuscript , DOI: 10.1039/C8MO00172C

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