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Etching silver nanoparticles by DNA


While DNA has been widely used for directing the growth and assembly of nanomaterials, the reverse reaction, etching nanoparticles by DNA has yet to be demonstrated. We herein communicate that poly-cytosine DNA (poly-C) can efficiently etch silver nanoparticles (AgNPs) followed by Ostwald ripening. The etching process was precisely controlled by varying the length, sequence, and concentration of DNA, and the number of consecutive cytosine is particularly important. In addition to spherical AgNPs, etching also occurred for silver nanoplates displaying interesting color changes. Compared to other chemical etching agents such as H2O2, Hg2+ and ferricyanide, DNA is highly biocompatible allowing biological applications. Poly-C DNA induced AgNP etching enhanced its cytotoxicity against cancer cells, and Gram-positive and Gram-negative bacterial cells. This study will stimulate many related work in DNA nanotechnology, bioanalytical sensors and nanomedicine.

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Publication details

The article was received on 11 Sep 2018, accepted on 09 Oct 2018 and first published on 09 Oct 2018

Article type: Communication
DOI: 10.1039/C8MH01126E
Citation: Mater. Horiz., 2018, Accepted Manuscript
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    Etching silver nanoparticles by DNA

    S. Hu, T. Yi, Z. Huang, B. Liu, J. Wang, X. Yi and J. Liu, Mater. Horiz., 2018, Accepted Manuscript , DOI: 10.1039/C8MH01126E

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