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Issue 3, 2018
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An electrochemical oxidative homo-coupling reaction of imidazopyridine heterocycles to biheteroaryls

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Abstract

An electrochemical dehydrogenative homo-coupling reaction of imidazopyridine-based heterocycles has been developed, which affords biheteroaryls with good chemical yields and high regioselectivities. This reaction is conducted in a simple undivided cell at room temperature, which avoids the use of any metal-catalysts, additives and oxidants. This reaction tolerates a wide scope of substrates, which provides an easy and green strategy for the preparation of important bioactive biheteroaryl compounds.

Graphical abstract: An electrochemical oxidative homo-coupling reaction of imidazopyridine heterocycles to biheteroaryls

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Article information


Submitted
26 Nov 2017
Accepted
04 Jan 2018
First published
16 Jan 2018

Green Chem., 2018,20, 583-587
Article type
Communication

An electrochemical oxidative homo-coupling reaction of imidazopyridine heterocycles to biheteroaryls

Y. Gao, Y. Wang, J. Zhou, H. Mei and J. Han, Green Chem., 2018, 20, 583
DOI: 10.1039/C7GC03563B

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