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Issue 11, 2018
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Effects of casein non-phosphopeptide on the development of rat muscle analyzed using computed tomography scanning technology

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Abstract

The effects of casein non-phosphopeptide (CNPP) on the muscle development of healthy rats and selected blood hormones levels were investigated. CT technology and the ELISA kit were employed to detect the cross-sectional area of each muscle group and blood hormone levels, respectively. The cross-sectional area of the trunk and lower limb muscles of resistance exercise group (REG) rats that were administered a high daily dose of CNPP for 50 days increased more significantly than that of the blank group rats, no exercise group (NEG) rats administered with the same daily dose of CNPP, and REG rats administered with the same daily dose of lactalbumin (P < 0.05).The more enhanced development of trunk and lower limb muscles in CNPP-administered REG rats was associated with a higher blood level of insulin, while no clear trends in blood levels of growth hormone and testosterone were observed. The present results have demonstrated that a combination of physical exercise and diet supplementation with CNPP can synergistically improve muscle mass.

Graphical abstract: Effects of casein non-phosphopeptide on the development of rat muscle analyzed using computed tomography scanning technology

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Publication details

The article was received on 17 Jul 2018, accepted on 06 Oct 2018 and first published on 17 Oct 2018


Article type: Paper
DOI: 10.1039/C8FO01405A
Citation: Food Funct., 2018,9, 5805-5812
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    Effects of casein non-phosphopeptide on the development of rat muscle analyzed using computed tomography scanning technology

    Y. Shi, N. Zhang, Q. Guo, H. Guan, S. Ikeda, C. Guo, W. Piekoszewski, T. K. Kalenik and E. Motkina, Food Funct., 2018, 9, 5805
    DOI: 10.1039/C8FO01405A

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