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Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

Abstract

Strategies to avoid lactose malabsorption, which affects 70% of the world's population, are focused on the restriction of milk and dairy products or the use of non-human β-galactosidases or probiotics endowed with β-galactosidase activity added at mealtime. The evaluation of a commercial blend of probiotics and enzymes (protease, lactase, lipase and amylase) and its potential application in lactase non-persistence management are described in this work. Recommended daily amounts (460-1000 mg) of commercial probiotics/enzymes blend showed to be adequate for in vitro lactose hydrolysis in standard solutions (0.25-5 %) and commercial dairy products, milk (5% lactose) and yogurts (3% lactose) reaching hydrolysis values between 44-96%. According to these percentages, the use of the enzymatic preparation would guarantee the intake of less than 12 g, recommendations of the EFSA for lactose intolerant. Furthermore, formation of prebiotic galactooligosaccharides was also detected increasing the potential benefits of the enzymatic preparation in the gastrointestinal system

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Publication details

The article was received on 31 May 2018, accepted on 30 Jul 2018 and first published on 02 Aug 2018


Article type: Paper
DOI: 10.1039/C8FO01091A
Citation: Food Funct., 2018, Accepted Manuscript
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    Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

    A. Ferreira, F. J. Moreno and M. Villamiel, Food Funct., 2018, Accepted Manuscript , DOI: 10.1039/C8FO01091A

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