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Issue 9, 2018
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Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

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Abstract

Strategies to avoid lactose malabsorption, which affects 70% of the world's population, are focused on the restriction of milk and dairy products or the use of non-human β-galactosidases or probiotics endowed with β-galactosidase activity added at mealtime. Our evaluation of a commercial blend of probiotics and enzymes (protease, lactase, lipase and amylase) and its potential application in lactase non-persistence management is described in this work. Recommended amounts (460–1000 mg) of the commercial probiotics–enzyme blend were shown to be adequate for performing in vitro lactose hydrolysis in standard solutions (0.25–5%) and commercial dairy products, namely milks (5% lactose) and yogurts (3% lactose), reaching hydrolysis values between 44 and 96%. According to these percentages, the use of the enzymatic preparation would guarantee the intake of less than 12 g, the recommendation of the EFSA for lactose intolerance. Furthermore, formation of prebiotic galactooligosaccharides was also detected, increasing the potential benefits of the enzymatic preparation in the gastrointestinal system.

Graphical abstract: Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

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Publication details

The article was received on 31 May 2018, accepted on 30 Jul 2018 and first published on 02 Aug 2018


Article type: Paper
DOI: 10.1039/C8FO01091A
Citation: Food Funct., 2018,9, 4642-4650
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    Application of a commercial digestive supplement formulated with enzymes and probiotics in lactase non-persistence management

    A. Ferreira-Lazarte, F. J. Moreno and M. Villamiel, Food Funct., 2018, 9, 4642
    DOI: 10.1039/C8FO01091A

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