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Issue 10, 2018
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Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties

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Abstract

Edible bird's nest (EBN), an Asian health food, contains insoluble proteins and conjugated N-acetylneuraminic acid (NANA) that are difficult to be absorbed by humans. In order to increase the nutritional value of EBN, we developed methods to digest EBN targeting the release of proteins and NANA. By using simulated gastric fluid under acidic conditions, the complex proteins were fully digested into smaller peptides, and in parallel, NANA was fully released from the conjugated form. The completely digested EBN showed better nutraceutical properties. In a skin whitening test, the EBN digest showed stronger inhibition of melanogenesis of cultured B16 cells and enzymatic activity of tyrosinase, as compared to that of undigested EBN. In addition, the EBN digest exhibited stronger osteogenic activity in cultured osteoblasts. Thus, the complete digestion of EBN could be applied to the development of a new generation of EBN health food products, including EBN drinks and skincare products.

Graphical abstract: Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties

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Publication details

The article was received on 18 May 2018, accepted on 30 Aug 2018 and first published on 04 Sep 2018


Article type: Paper
DOI: 10.1039/C8FO00991K
Citation: Food Funct., 2018,9, 5139-5149

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    Complete digestion of edible bird's nest releases free N-acetylneuraminic acid and small peptides: an efficient method to improve functional properties

    Z. C. F. Wong, G. K. L. Chan, K. Q. Y. Wu, K. K. M. Poon, Y. Chen, T. T. X. Dong and K. W. K. Tsim, Food Funct., 2018, 9, 5139
    DOI: 10.1039/C8FO00991K

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