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Rhodium at the chemistry–biology interface

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Abstract

As a rare element with no known natural biological function, rhodium has a limited history in biological chemistry and chemical biology. However, rhodium complexes have unique structure and reactivity attributes, and chemists have increasingly used these attributes to probe and perturb living systems. This brief review focuses on recent advances in the use of rhodium complexes in biological contexts, including medicinal chemistry, protein science, and chemical biology. In particular, we highlight both structure- and reactivity-driven approaches to biological probes and discuss how coordination environment affects molecular properties in a biological environment.

Graphical abstract: Rhodium at the chemistry–biology interface

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Publication details

The article was received on 24 Jul 2018, accepted on 13 Sep 2018 and first published on 14 Sep 2018


Article type: Frontier
DOI: 10.1039/C8DT03032D
Citation: Dalton Trans., 2018, Advance Article
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    Rhodium at the chemistry–biology interface

    J. Ohata and Z. T. Ball, Dalton Trans., 2018, Advance Article , DOI: 10.1039/C8DT03032D

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