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Issue 44, 2018
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A novel mesoionic carbene based highly fluorescent Pd(II) complex as an endoplasmic reticulum tracker in live cells

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Abstract

A recent study advocates that endoplasmic reticulum (ER) dysfunction may be linked to critical neurotrauma and advanced tauopathy. In this regard, targeting the ER warrants urgent attention towards the therapeutic treatment of neurotrauma-related neurodegeneration. Herein, we report the synthesis of a new N-heterocyclic mesoionic carbene based highly fluorescent square-planar Pd(II) complex 1, with a high quantum yield (0.737). Probe 1 is a non-toxic probe for selectively labeling the endoplasmic reticulum in live cells.

Graphical abstract: A novel mesoionic carbene based highly fluorescent Pd(ii) complex as an endoplasmic reticulum tracker in live cells

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Publication details

The article was received on 06 Jul 2018, accepted on 29 Aug 2018 and first published on 30 Aug 2018


Article type: Communication
DOI: 10.1039/C8DT02778A
Citation: Dalton Trans., 2018,47, 15646-15650
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    A novel mesoionic carbene based highly fluorescent Pd(II) complex as an endoplasmic reticulum tracker in live cells

    S. K. Verma, P. Kumari, S. N. Ansari, M. O. Ansari, D. Deori and S. M. Mobin, Dalton Trans., 2018, 47, 15646
    DOI: 10.1039/C8DT02778A

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