Jump to main content
Jump to site search

Issue 32, 2018
Previous Article Next Article

Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase

Author affiliations

Abstract

Ferritin, a naturally occuring iron-storage protein, plays an important role in nanoengineering and biomedical applications. Upon iron removal, apoferritin was shown to allow the encapsulation of an artificial transfer hydrogenase (ATHase) based on the streptavidin-biotin technology. The third coordination sphere, provided by ferritin, significantly influences the catalytic activity of an ATHase for the reduction of cyclic imines.

Graphical abstract: Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase

Back to tab navigation

Supplementary files

Article information


Submitted
31 May 2018
Accepted
10 Jul 2018
First published
11 Jul 2018

Dalton Trans., 2018,47, 10837-10841
Article type
Communication

Ferritin encapsulation of artificial metalloenzymes: engineering a tertiary coordination sphere for an artificial transfer hydrogenase

M. Hestericová, T. Heinisch, M. Lenz and T. R. Ward, Dalton Trans., 2018, 47, 10837
DOI: 10.1039/C8DT02224K

Social activity

Search articles by author

Spotlight

Advertisements