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Stimuli-responsive metal–organic supercontainers as synthetic proton receptors

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Abstract

We demonstrate a proof-of-concept design of a new platform for proton recognition and modulation. The new proton receptors are derived from a unique class of synthetic supercontainers that exhibit exceptional proton binding capacity (over 50 equiv.) and intriguing proton-dependent fluorescent switching behavior. Experimental and computational studies suggest that the proton-responsive event involves a two-step mechanism pertaining to proton binding by both amino and pyrenyl moieties of the supercontainer constructs. The high proton binding capacity of the supercontainers can be further modulated via small-molecule “regulators” that compete for the proton-binding sites, opening exiting new opportunities for proton manipulation in both chemistry and biology.

Graphical abstract: Stimuli-responsive metal–organic supercontainers as synthetic proton receptors

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Publication details

The article was received on 11 May 2018, accepted on 07 Jul 2018 and first published on 09 Jul 2018


Article type: Paper
DOI: 10.1039/C8DT01900B
Citation: Dalton Trans., 2018, Advance Article
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    Stimuli-responsive metal–organic supercontainers as synthetic proton receptors

    C. Sun, L. Cheng, Y. Qiao, L. Zhang, Z. Chen, F. Dai, W. Lin and Z. Wang, Dalton Trans., 2018, Advance Article , DOI: 10.1039/C8DT01900B

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