Jump to main content
Jump to site search

Issue 12, 2018
Previous Article Next Article

Chirality in metal-based anticancer agents

Author affiliations


Chiral natural biological molecules, such as nucleic acids and proteins, guide the research of chiral compounds. Chiral metal-based drugs are currently an interesting and rapidly growing field in anticancer research. This perspective focuses on chiral metal compounds with application in cancer chemotherapy. The different chiral metal-based anticancer agents and the extent to which the chiral resolution affects their biological properties are discussed. This perspective will aid the design of new potent and efficient chiral metal-based anticancer drugs that exploit their unique properties combined with their potential selectivity toward targeted chiral biomolecules.

Graphical abstract: Chirality in metal-based anticancer agents

Back to tab navigation

Publication details

The article was received on 09 Jan 2018, accepted on 07 Feb 2018 and first published on 08 Feb 2018

Article type: Perspective
DOI: 10.1039/C8DT00089A
Citation: Dalton Trans., 2018,47, 4017-4026
  •   Request permissions

    Chirality in metal-based anticancer agents

    Y. Wang, H. Huang, Q. Zhang and P. Zhang, Dalton Trans., 2018, 47, 4017
    DOI: 10.1039/C8DT00089A

Search articles by author