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Issue 46, 2018
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Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

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Abstract

Encapsulating well-defined nanoparticles (NPs) into ZIF-8 to form core–shell structures not only can minimize the drawbacks and maximize the advantages of the disparate components but also may provide synergistic functionality. This work presents novel one-pot synthetic methods to produce Fe3O4@ZIF-8 NPs. Moreover, the morphology of Fe3O4@ZIF-8 NPs can be easily controlled by changing the synthesis conditions (time, temperature, and dosage). The as-obtained Fe3O4@ZIF-8 NPs have good dispersibility and a large specific surface area and they are proven to have potential applications as drug delivery models with good biocompatibility, high drug loading and good pH responsiveness.

Graphical abstract: Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

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Publication details

The article was received on 04 Aug 2018, accepted on 08 Oct 2018 and first published on 09 Oct 2018


Article type: Paper
DOI: 10.1039/C8CE01302K
Citation: CrystEngComm, 2018,20, 7486-7491
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    Controlled synthesis of Fe3O4@ZIF-8 nanoparticles for drug delivery

    G. Chen, B. Yu, C. Lu, H. Zhang, Y. Shen and H. Cong, CrystEngComm, 2018, 20, 7486
    DOI: 10.1039/C8CE01302K

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