Jump to main content
Jump to site search

Issue 99, 2018
Previous Article Next Article

Imaging of intracellular-specific microRNA in tumor cells by symmetric exponential amplification-assisted fluorescence in situ hybridization

Author affiliations

Abstract

We report a symmetric exponential amplification-assisted fluorescence in situ hybridization (SEXPAR-FISH) strategy for imaging intracellular-specific microRNAs (miRNAs) in cells. The strategy eliminates the risk of cell loss and miRNA leakage, and low-abundant intracellular miR-27a in cells can be imaged in only 2 h without compromising sensitivity and specificity.

Graphical abstract: Imaging of intracellular-specific microRNA in tumor cells by symmetric exponential amplification-assisted fluorescence in situ hybridization

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Nov 2018, accepted on 15 Nov 2018 and first published on 15 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08849G
Citation: Chem. Commun., 2018,54, 13981-13984
  •   Request permissions

    Imaging of intracellular-specific microRNA in tumor cells by symmetric exponential amplification-assisted fluorescence in situ hybridization

    J. Chen, W. Yin, Y. Ma, H. Yang, Y. Zhang, M. Xu, X. Zheng, Z. Dai and X. Zou, Chem. Commun., 2018, 54, 13981
    DOI: 10.1039/C8CC08849G

Search articles by author

Spotlight

Advertisements