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Issue 99, 2018
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Tracking mitochondrial 1O2-ROS production through a differential mitochondria-nucleoli fluorescent probe

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Abstract

The dual-emissive fluorescent probe described here enabled dynamic tracking of singlet oxygen (1O2)-ROS species production and localization dynamics between the mitochondria and nucleoli in the presence of agents perturbing the mitochondrial membrane potential and under a photodynamic (PDT) system. Local structural information during the probe-1O2 interaction was followed by spectrally resolved confocal microscopy.

Graphical abstract: Tracking mitochondrial 1O2-ROS production through a differential mitochondria-nucleoli fluorescent probe

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Publication details

The article was received on 16 Oct 2018, accepted on 13 Nov 2018 and first published on 13 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08289H
Citation: Chem. Commun., 2018,54, 13997-14000
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    Tracking mitochondrial 1O2-ROS production through a differential mitochondria-nucleoli fluorescent probe

    R. Flores-Cruz and A. Jiménez-Sánchez, Chem. Commun., 2018, 54, 13997
    DOI: 10.1039/C8CC08289H

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