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Issue 96, 2018
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Copper-catalyzed oxidative intermolecular 1,2-alkylarylation of styrenes with ethers and indoles

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Abstract

A new copper-catalyzed oxidative three-component intermolecular 1,2-alkylarylation of styrenes with ethers and indoles is disclosed. This method utilizes TBPB as an oxidant to efficiently construct C(sp3)–C(sp3) and C(sp3)–C(sp2) bonds in one step through probable radical and electrophilic alkylation processes, respectively, and a variety of functional groups are well tolerated.

Graphical abstract: Copper-catalyzed oxidative intermolecular 1,2-alkylarylation of styrenes with ethers and indoles

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Publication details

The article was received on 16 Oct 2018, accepted on 05 Nov 2018 and first published on 06 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08274J
Citation: Chem. Commun., 2018,54, 13511-13514

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    Copper-catalyzed oxidative intermolecular 1,2-alkylarylation of styrenes with ethers and indoles

    R. Su, Y. Li, M. Min, X. Ouyang, R. Song and J. Li, Chem. Commun., 2018, 54, 13511
    DOI: 10.1039/C8CC08274J

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