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Issue 97, 2018
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The other side of the superoxide radical anion: its ability to chemically repair DNA oxidized sites

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Abstract

The superoxide radical anion can repair oxidative damage. In particular, it was demonstrated that O2˙ can repair oxidized DNA by electron transfer, restoring the original structure of this important molecule. Acid–base equilibria have been considered, and the influence of the pH on the main reaction mechanism has been explored.

Graphical abstract: The other side of the superoxide radical anion: its ability to chemically repair DNA oxidized sites

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Article information


Submitted
30 Sep 2018
Accepted
12 Nov 2018
First published
12 Nov 2018

Chem. Commun., 2018,54, 13710-13713
Article type
Communication

The other side of the superoxide radical anion: its ability to chemically repair DNA oxidized sites

L. Muñoz-Rugeles, A. Galano and J. R. Alvarez-Idaboy, Chem. Commun., 2018, 54, 13710
DOI: 10.1039/C8CC07834C

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