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A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting H2S and various thiol species in solution and in live cells

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Abstract

A novel dual-channel fluorescent probe (NCR) based on differences in reactivity among H2S, Cys/Hcy, and GSH was rationally designed for simultaneously distinguishing and sequentially sensing H2S, Cys/Hcy, and GSH using two emission channels, which also demonstrated that NCR can be used for targeting mitochondria in mammalian cells.

Graphical abstract: A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting H2S and various thiol species in solution and in live cells

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Publication details

The article was received on 28 Sep 2018, accepted on 01 Nov 2018 and first published on 01 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC07761D
Citation: Chem. Commun., 2018, Advance Article
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    A highly selective and sensitive fluorescent probe for simultaneously distinguishing and sequentially detecting H2S and various thiol species in solution and in live cells

    D. Qiao, T. Shen, M. Zhu, X. Liang, L. Zhang, Z. Yin, B. Wang and L. Shang, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC07761D

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