Jump to main content
Jump to site search

Issue 87, 2018
Previous Article Next Article

Dual-channel near-infrared fluorescent probe for real-time tracking of endogenous γ-glutamyl transpeptidase activity

Author affiliations

Abstract

A curcuminoid difluoroboron-based tumor-targeting GGT-activatable fluorescent probe (Glu-DFB-biotin) is designed, which has remarkable characteristics of dual-channel and light-up near-infrared (NIR) fluorescence. Furthermore, Glu-DFB-biotin can differentiate hepatic cancer cells from normal cells and is successfully employed for real-time tracking of endogenous GGT activity in living cells.

Graphical abstract: Dual-channel near-infrared fluorescent probe for real-time tracking of endogenous γ-glutamyl transpeptidase activity

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Sep 2018, accepted on 03 Oct 2018 and first published on 04 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC07376G
Citation: Chem. Commun., 2018,54, 12393-12396

  •   Request permissions

    Dual-channel near-infrared fluorescent probe for real-time tracking of endogenous γ-glutamyl transpeptidase activity

    B. Bai, C. Yan, Y. Zhang, Z. Guo and W. Zhu, Chem. Commun., 2018, 54, 12393
    DOI: 10.1039/C8CC07376G

Search articles by author

Spotlight

Advertisements