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Issue 83, 2018
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Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

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Abstract

To address the challenges associated with glycan analyses, we have implemented a structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended routing (SUPER) ion mobility-mass spectrometry (i.e. SLIM SUPER IM-MS) platform to achieve much higher resolution of isomeric glycoforms. We have demonstrated the potential of this platform as a future component of the glycomics toolbox.

Graphical abstract: Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

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Publication details

The article was received on 27 Aug 2018, accepted on 21 Sep 2018 and first published on 25 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06966B
Citation: Chem. Commun., 2018,54, 11701-11704
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    Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

    G. Nagy, I. K. Attah, S. V. B. Garimella, K. Tang, Y. M. Ibrahim, E. S. Baker and R. D. Smith, Chem. Commun., 2018, 54, 11701
    DOI: 10.1039/C8CC06966B

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