Jump to main content
Jump to site search

Issue 80, 2018
Previous Article Next Article

ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND’ biological thiols

Author affiliations

Abstract

An ESIPT-based ‘AND’ logic fluorescence probe (GSH-ABAH) was developed for the simultaneous detection of ONOO and biological thiols. GSH-ABAH was shown to have good cell permeability and with the addition of just SIN-1 (ONOO donor) or GSH, no fluorescence response was observed in live cells. However, in the presence of both analytes GSH-ABAH could be used to image exogenous ONOO ‘AND’ GSH added to RAW264.7 cells.

Graphical abstract: ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND’ biological thiols

Back to tab navigation

Supplementary files

Publication details

The article was received on 25 Aug 2018, accepted on 11 Sep 2018 and first published on 11 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06917D
Citation: Chem. Commun., 2018,54, 11336-11339
  • Open access: Creative Commons BY license
  •   Request permissions

    ESIPT-based fluorescence probe for the rapid detection of peroxynitrite ‘AND’ biological thiols

    L. Wu, H. Han, L. Liu, J. E. Gardiner, A. C. Sedgwick, C. Huang, S. D. Bull, X. He and T. D. James, Chem. Commun., 2018, 54, 11336
    DOI: 10.1039/C8CC06917D

    This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.

    Reproduced material should be attributed as follows:

    • For reproduction of material from NJC:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
    • For reproduction of material from PCCP:
      [Original citation] - Published by the PCCP Owner Societies.
    • For reproduction of material from PPS:
      [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
    • For reproduction of material from all other RSC journals:
      [Original citation] - Published by The Royal Society of Chemistry.

    Information about reproducing material from RSC articles with different licences is available on our Permission Requests page.

Search articles by author

Spotlight

Advertisements