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Aggregation-induced near-infrared emitting platinum(II) terpyridyl complex: cellular characterisation and lysosome-specific localisation

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Abstract

A novel near-infrared luminogen (TPE/TPY-Pt-PA/PEG) based on the terpyridyl Pt(II) complex with a tetraphenylethene periphery is synthesised and characterised. It displays aggregation-induced emission with the formation of self-assembled nanostructures. The nanoparticles fabricated with TPE/TPY-Pt-PA/PEG show excellent biocompatibility with high specificity to lysosomes in HeLa cells.

Graphical abstract: Aggregation-induced near-infrared emitting platinum(ii) terpyridyl complex: cellular characterisation and lysosome-specific localisation

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Publication details

The article was received on 22 Aug 2018, accepted on 07 Sep 2018 and first published on 10 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06839A
Citation: Chem. Commun., 2018, Advance Article
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    Aggregation-induced near-infrared emitting platinum(II) terpyridyl complex: cellular characterisation and lysosome-specific localisation

    J. Wu, Y. Li, C. Tan, X. Wang, Y. Zhang, J. Song, J. Qu and W. Wong, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06839A

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