Issue 94, 2018
From the journal:

Chemical Communications

Dual-modal in vivo fluorescence and photoacoustic imaging using a heterodimeric peptide†

Jing Chen, ORCID logo a   Zhenghong Gao,a   Gaoming Lib  and  Thomas D. Wang ORCID logo *abc  

* Corresponding authors

a Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

b Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA

c Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, USA
E-mail: thomaswa@umich.edu
Fax: +1-734-647-7950
Tel: +1-734-936-1228

Abstract

A heterodimeric peptide labeled with IRDye800 is used to perform dual-modal imaging of human esophageal xenograft tumors in vivo. Fluorescence and photoacoustic images provide complementary visualization of tumor dimensions in planar and sagittal views, respectively, demonstrating promise for targeted cancer diagnosis and staging.

Graphical abstract: Dual-modal in vivo fluorescence and photoacoustic imaging using a heterodimeric peptide

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Article information

DOI
https://doi.org/10.1039/C8CC06774K
Article type
Communication
Submitted
21 Aug 2018
Accepted
08 Oct 2018
First published
08 Oct 2018

Chem. Commun., 2018,54, 13196-13199

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Dual-modal in vivo fluorescence and photoacoustic imaging using a heterodimeric peptide

J. Chen, Z. Gao, G. Li and T. D. Wang, Chem. Commun., 2018, 54, 13196 DOI: 10.1039/C8CC06774K

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