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Asynchrony of spectral blue-shifts of quantum dot based digital homogeneous immunoassay

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Abstract

A femtomolar digital homogenous immunoassay is developed based on sensitively distinguishing the immunocomplexes labeled with quantum dot (QD) aggregates from the excessive free monodisperse single QDs. The success in quantifying the carcino-embryonic antigen and alpha-fetoprotein in plasma validated the feasibility of our approach for clinical tests.

Graphical abstract: Asynchrony of spectral blue-shifts of quantum dot based digital homogeneous immunoassay

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Publication details

The article was received on 20 Aug 2018, accepted on 29 Oct 2018 and first published on 29 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC06754F
Citation: Chem. Commun., 2018, Advance Article
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    Asynchrony of spectral blue-shifts of quantum dot based digital homogeneous immunoassay

    X. Liu, C. Huang, X. Dong, A. Liang, Y. Zhang, Q. Zhang, Q. Wang and H. Gai, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06754F

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