Jump to main content
Jump to site search


Arylation of benzyl amines with aromatic nitriles

Author affiliations

Abstract

In the past years, the activations of aromatic nitriles for radical arylations under photoirradiation have been developed. We here report the first example of radical arylations using aromatic nitriles without the assistance of photoirradiation. Importantly, with this method, the direct arylation of C(sp3)–H in benzyl amines provided a practical method for the synthesis of diarylmethylamines without the use of precious transition metal catalysts.

Graphical abstract: Arylation of benzyl amines with aromatic nitriles

Back to tab navigation

Supplementary files

Publication details

The article was received on 06 Aug 2018, accepted on 24 Sep 2018 and first published on 25 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06408C
Citation: Chem. Commun., 2018, Advance Article
  •   Request permissions

    Arylation of benzyl amines with aromatic nitriles

    Y. Lei, J. Yang, R. Qi, S. Wang, R. Wang and Z. Xu, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06408C

Search articles by author

Spotlight

Advertisements