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Novel chiral halogen and chalcogen bonding receptors exhibit different selectivities for stereo- and geometric dicarboxylate isomers compared to a hydrogen bonding analogue. The unique geometric and electronic properties of the chalcogen bonding receptor facilitate the diagnostic fluorescence sensing of geometric dicarboxylate isomer guest species.

Graphical abstract: Chiral halogen and chalcogen bonding receptors for discrimination of stereo- and geometric dicarboxylate isomers in aqueous media

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