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Variation in the Yaa position of collagen peptides containing azaGlycine

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Abstract

Herein, we report the systematic investigation of amino acid variation in the Yaa position of collagen peptides containing an adjacent azaGlycine residue. We demonstrate the reliability of azaGlycine as a glycine replacement and provide a sequence independent strategy for stabilizing the triple helical assembly of collagen peptides.

Graphical abstract: Variation in the Yaa position of collagen peptides containing azaGlycine

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Publication details

The article was received on 04 Aug 2018, accepted on 28 Sep 2018 and first published on 05 Oct 2018


Article type: Communication
DOI: 10.1039/C8CC06372A
Citation: Chem. Commun., 2018, Advance Article
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    Variation in the Yaa position of collagen peptides containing azaGlycine

    S. D. Melton and D. M. Chenoweth, Chem. Commun., 2018, Advance Article , DOI: 10.1039/C8CC06372A

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