Jump to main content
Jump to site search

Issue 83, 2018
Previous Article Next Article

Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

Author affiliations

Abstract

Tumor biomarkers are highly desirable for the screening of patients with a risk of tumor development and progression. Here, we report a beta-galactosidase (β-gal)-responsive acetaminophen (β-GR-APAP) as a synthetic plasma biomarker for targeted tumor detection. Tumor β-gal labeling via the recognition of tumor-related antigen enabled the detection of a tumor using β-GR-APAP.

Graphical abstract: Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

Back to tab navigation

Supplementary files

Publication details

The article was received on 26 Jul 2018, accepted on 17 Sep 2018 and first published on 26 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC06068A
Citation: Chem. Commun., 2018,54, 11745-11748
  •   Request permissions

    Beta-galactosidase-responsive synthetic biomarker for targeted tumor detection

    T. Nishihara, S. Kuno, H. Nonaka, S. Tabata, N. Saito, S. Fukuda, M. Tomita, S. Sando and T. Soga, Chem. Commun., 2018, 54, 11745
    DOI: 10.1039/C8CC06068A

Search articles by author

Spotlight

Advertisements