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Issue 81, 2018
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DNA nanoflower blooms in nanochannels: a new strategy for miRNA detection

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Abstract

By employing DNA nanoflower blooming in the nanochannels of porous anodic alumina (PAA), a nanochannel platform for microRNA (miRNA) detection has been proposed. Significant steric and electrostatic hindrance of the miRNA-initiated DNA-nanoflower growth may also amplify the signal readout for miRNA detection to give excellent sensitivity, selectivity and reproducibility.

Graphical abstract: DNA nanoflower blooms in nanochannels: a new strategy for miRNA detection

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Publication details

The article was received on 13 Jul 2018, accepted on 29 Aug 2018 and first published on 30 Aug 2018


Article type: Communication
DOI: 10.1039/C8CC05690K
Citation: Chem. Commun., 2018,54, 11391-11394
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    DNA nanoflower blooms in nanochannels: a new strategy for miRNA detection

    L. Shi, C. Mu, T. Gao, T. Chen, S. Hei, J. Yang and G. Li, Chem. Commun., 2018, 54, 11391
    DOI: 10.1039/C8CC05690K

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