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Hemiaminal ether linkages provide a selective release of payloads from polymer conjugates

Abstract

We introduce here hemiaminal ether linkages, synthesized from coupling a vinyl ether and a 1,2,3-triazole, as responsive group in polymers to allow the selective release of a functional molecule. Release kinetics of benzotriazole from polymer nanoparticles shows a fast release at low pH values and a prolongated or even no release in mild acidic conditions and at neutral pH.

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Publication details

The article was received on 04 Jul 2018, accepted on 07 Nov 2018 and first published on 07 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC05386C
Citation: Chem. Commun., 2018, Accepted Manuscript
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    Hemiaminal ether linkages provide a selective release of payloads from polymer conjugates

    F. Seidi, V. Druet, N. Huynh, T. Pakkeeree and D. Crespy, Chem. Commun., 2018, Accepted Manuscript , DOI: 10.1039/C8CC05386C

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