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Issue 67, 2018
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Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide

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Abstract

Antimicrobial functionality is introduced into a pharmaceutical formulation of miconazole while improving solubility. The work leverages hydrate formation propensity in order to produce hydrogen peroxide solvates. The ubiquity of hydrate formation suggests that hydrogen peroxide can be broadly deployed in pharmaceuticals, rendering a liquid excipient suitable for solid pharmaceutical formulations.

Graphical abstract: Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide

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Publication details

The article was received on 06 Jun 2018, accepted on 23 Jul 2018 and first published on 26 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04530E
Citation: Chem. Commun., 2018,54, 9286-9289
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    Pharmaceutical solvate formation for the incorporation of the antimicrobial agent hydrogen peroxide

    K. M. Kersten, M. E. Breen, A. K. Mapp and A. J. Matzger, Chem. Commun., 2018, 54, 9286
    DOI: 10.1039/C8CC04530E

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