Issue 64, 2018

Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

Abstract

A novel proximity induced transcription assay for highly sensitive protein detection based on protein mediated ligation of a DNA template with the transcription of a light-up RNA aptamer for signal amplification has been developed.

Graphical abstract: Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

Supplementary files

Article information

Article type
Communication
Submitted
06 Jun 2018
Accepted
10 Jul 2018
First published
13 Jul 2018

Chem. Commun., 2018,54, 8877-8880

Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

Z. Ying, H. Xiao, H. Tang, R. Yu and J. Jiang, Chem. Commun., 2018, 54, 8877 DOI: 10.1039/C8CC04498H

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