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Issue 64, 2018
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Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

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Abstract

A novel proximity induced transcription assay for highly sensitive protein detection based on protein mediated ligation of a DNA template with the transcription of a light-up RNA aptamer for signal amplification has been developed.

Graphical abstract: Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

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Publication details

The article was received on 06 Jun 2018, accepted on 10 Jul 2018 and first published on 13 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC04498H
Citation: Chem. Commun., 2018,54, 8877-8880
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    Light-up RNA aptamer enabled label-free protein detection via a proximity induced transcription assay

    Z. Ying, H. Xiao, H. Tang, R. Yu and J. Jiang, Chem. Commun., 2018, 54, 8877
    DOI: 10.1039/C8CC04498H

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