Chun-Hua Yang, Xixi Chen, Huimin Li, Wenbo Wei, Zhantao Yang and Junbiao Chang
Chem. Commun., 2018,54, 8622-8625
DOI:
10.1039/C8CC04262D,
Communication
A reduction of quinolines to synthetically versatile tetrahydroquinoline molecules with I2 and HBpin is described. In the presence of iodine (20 mol%) as a catalyst, reduction of quinolines and other N-heteroarenes proceeded readily with hydroboranes as the reducing reagents. The broad functional-group tolerance, good yields and mild reaction conditions imply high practical utility.
