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Issue 69, 2018
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A tumor-targeting probe based on a mitophagy process for live imaging

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Abstract

A glucosamine modified near-infrared cyanine dye CyT sensitive to pH was synthesized. Due to the different pH values of mitochondria and autolysosomes, the probe can simultaneously investigate mitochondria and autolysosomes in living cells. Moreover, due to the introduction of glucosamine groups, this fluorescent probe can be applied for tumor targeted imaging.

Graphical abstract: A tumor-targeting probe based on a mitophagy process for live imaging

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Publication details

The article was received on 28 May 2018, accepted on 02 Aug 2018 and first published on 04 Aug 2018


Article type: Communication
DOI: 10.1039/C8CC04246B
Citation: Chem. Commun., 2018,54, 9675-9678
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    A tumor-targeting probe based on a mitophagy process for live imaging

    L. Gui, Z. Yuan, H. Kassaye, J. Zheng, Y. Yao, F. Wang, Q. He, Y. Shen, L. Liang and H. Chen, Chem. Commun., 2018, 54, 9675
    DOI: 10.1039/C8CC04246B

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