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Issue 51, 2018
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Raman fingerprints of amyloid structures

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Structural differences in pathological and functional amyloid fibrils have been investigated by Raman microspectroscopy. Second-derivative analyses of amide-I and amide-III bands distinguish parallel in-register β-sheets from a β-solenoid. Further, spatially resolved Raman spectra reveal molecular heterogeneity in amyloid structures.

Graphical abstract: Raman fingerprints of amyloid structures

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The article was received on 20 Apr 2018, accepted on 08 May 2018 and first published on 14 May 2018

Article type: Communication
DOI: 10.1039/C8CC03217C
Citation: Chem. Commun., 2018,54, 6983-6986
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    Raman fingerprints of amyloid structures

    J. D. Flynn and J. C. Lee, Chem. Commun., 2018, 54, 6983
    DOI: 10.1039/C8CC03217C

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