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Issue 33, 2018
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Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base–Ru(ii)–curcumin organometallic conjugate

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Abstract

The synthesis, photophysics and biological investigation of fluorescent 4-amino-1,8-naphthalimide Tröger's bases (TB-1–TB-3) and a new Tröger's base p-cymene–Ru(II)–curcumin organometallic conjugate (TB–Ru–Cur) are described; these compounds showed fast cellular uptake and displayed good luminescence and cytotoxicity against cervical cancer cells.

Graphical abstract: Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base–Ru(ii)–curcumin organometallic conjugate

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Article information


Submitted
26 Feb 2018
Accepted
29 Mar 2018
First published
29 Mar 2018

Chem. Commun., 2018,54, 4120-4123
Article type
Communication

Synthesis, structural characterisation and antiproliferative activity of a new fluorescent 4-amino-1,8-naphthalimide Tröger's base–Ru(II)–curcumin organometallic conjugate

S. Shanmugaraju, B. la Cour Poulsen, T. Arisa, D. Umadevi, H. L. Dalton, C. S. Hawes, S. Estalayo-Adrián, A. J. Savyasachi, G. W. Watson, D. C. Williams and T. Gunnlaugsson, Chem. Commun., 2018, 54, 4120
DOI: 10.1039/C8CC01584H

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