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Issue 30, 2018
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Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging

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Abstract

A new physiologically benign and cell membrane permeable BODIPY based molecular probe, MB-Sn, specifically senses intracellular hydrogen polysulfides (H2Sn, n > 1) localized in the endoplasmic reticulum. This reagent is suitable for mapping the intracellular distribution of H2Sn by wide-field as well as super-resolution Structured Illumination Microscopy (SIM).

Graphical abstract: Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging

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Article information


Submitted
15 Feb 2018
Accepted
19 Mar 2018
First published
20 Mar 2018

Chem. Commun., 2018,54, 3735-3738
Article type
Communication

Polysulfide-triggered fluorescent indicator suitable for super-resolution microscopy and application in imaging

A. H. A., S. Sreedharan, F. Ali, C. G. Smythe, J. A. Thomas and A. Das, Chem. Commun., 2018, 54, 3735
DOI: 10.1039/C8CC01332B

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