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Issue 15, 2018
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A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

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Abstract

This communication reports on a fluorescent probe (PPI-P) for imaging active peptidyl-prolyl cis/trans isomerases in live cells. PPI-P is capable of responding to both recombinant and cellular PPIases fluorogenically, and has been shown to specifically image active PPIases in live cells.

Graphical abstract: A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

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Supplementary files

Article information


Submitted
28 Nov 2017
Accepted
23 Jan 2018
First published
23 Jan 2018

Chem. Commun., 2018,54, 1857-1860
Article type
Communication

A fluorescent peptidyl substrate for visualizing peptidyl-prolyl cis/trans isomerase activity in live cells

Q. Jiang, X. Li, C. Wang, J. Cheng, C. Tan, T. Cui, N. Lu, T. D. James, F. Han and X. Li, Chem. Commun., 2018, 54, 1857
DOI: 10.1039/C7CC09135D

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