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Issue 8, 2018
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A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

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Abstract

A one-pot fuel cell for specific, enzyme-catalysed organic synthesis, with continuous monitoring of rate and reaction progress, combines an electrode catalysing rapid, reversible and diffusion-controlled interconversion of NADP+ and NADPH with a Pt electrode catalysing 2H+/H2 interconversion. This Communication demonstrates its performance and characteristics using the reductive amination of 2-oxoglutarate as a test system.

Graphical abstract: A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

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Article information


Submitted
17 Nov 2017
Accepted
02 Jan 2018
First published
10 Jan 2018

Chem. Commun., 2018,54, 972-975
Article type
Communication

A hydrogen fuel cell for rapid, enzyme-catalysed organic synthesis with continuous monitoring

L. Wan, C. F. Megarity, B. Siritanaratkul and F. A. Armstrong, Chem. Commun., 2018, 54, 972 DOI: 10.1039/C7CC08859K

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