Issue 10, 2018
From the journal:

Biomaterials Science

Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation†

Yajie Zhang, ORCID logo ab   Hong Chen,c   Tingting Zhang, ORCID logo c   Yue Zan,c   Tianyu Ni,ad   Min Liu ORCID logo *ab  and  Renjun Pei ORCID logo *ab  

* Corresponding authors

a CAS Key Laboratory for Nano-Bio Interface, Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, China
E-mail: rjpei2011@sinano.ac.cn, mliu2010@sinano.ac.cn

b School of Nano Technology and Nano Bionics, University of Science and Technology of China, Hefei, China

c School of Pharmacy, Xi'an Jiaotong University, Xi'an, China

d Nano Science and Technology Institute, University of Science and Technology of China, Suzhou, China

Abstract

An injectable in situ fast-forming hydrogel was easily fabricated through the inverse electron demand Diels–Alder click reaction between trans-cyclooctene and tetrazine. This hydrogel system simultaneously encapsulated bone morphogenetic protein-2 and BMSCs which showed potential applications in 3D bio-printing and tissue engineering.

Graphical abstract: Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation

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Article information

DOI
https://doi.org/10.1039/C8BM00689J
Article type
Communication
Submitted
21 Jun 2018
Accepted
20 Aug 2018
First published
21 Aug 2018

Biomater. Sci., 2018,6, 2578-2581

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Fast-forming BMSC-encapsulating hydrogels through bioorthogonal reaction for osteogenic differentiation

Y. Zhang, H. Chen, T. Zhang, Y. Zan, T. Ni, M. Liu and R. Pei, Biomater. Sci., 2018, 6, 2578 DOI: 10.1039/C8BM00689J

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