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Issue 1, 2018
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SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

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Abstract

Although there is extensive literature covering the biomedical applications of superparamagnetic iron oxide nanoparticles (SPIONs), the phase of the iron oxide core used is not often taken into account when cell labelling and tracking studies for regenerative medicine are considered. Here, we use a co-precipitation reaction to synthesise particles of both magnetite- (Fe3O4) and maghemite- (γ-Fe2O3) based cores and consider whether the extra synthesis step to make maghemite based particles is advantageous for cell tracking.

Graphical abstract: SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

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Supplementary files

Article information


Submitted
13 Jun 2017
Accepted
23 Nov 2017
First published
23 Nov 2017

This article is Open Access

Biomater. Sci., 2018,6, 101-106
Article type
Communication

SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

M. Barrow, A. Taylor, A. M. Fuentes-Caparrós, J. Sharkey, L. M. Daniels, P. Mandal, B. K. Park, P. Murray, M. J. Rosseinsky and D. J. Adams, Biomater. Sci., 2018, 6, 101
DOI: 10.1039/C7BM00515F

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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the Centre National de la Recherche Scientifique (CNRS) and the RSC.
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    [Original citation] - Published by The Royal Society of Chemistry (RSC) on behalf of the European Society for Photobiology, the European Photochemistry Association, and RSC.
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    [Original citation] - Published by The Royal Society of Chemistry.

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