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Heavy metal ion discrimination based on distinct interaction between single-stranded DNA and methylene blue

Abstract

In this work, we develop a facile and extensible colorimetric sensor array based on the different interaction between methylene blue (MB) and single-stranded DNA (ssDNA) for the discrimination of heavy metal ions. Different target metal ions can make MB exhibit diversified color and absorbance changes in the presence of different DNA as receptors. Upon linear discriminant analysis (LDA), this result renders clear identification of each heavy metal ion on a two-dimensional (2D) spatial dispersion plot. Therefore, a new sensor array composed of three ssDNA as receptors and MB as a colorimetric probe is designed for fast discrimination of metal ions, which achieves the accurate discrimination of 9 species of heavy metal ions at 30 nM in buffer and tap water samples.

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Publication details

The article was received on 28 Sep 2018, accepted on 06 Nov 2018 and first published on 06 Nov 2018


Article type: Paper
DOI: 10.1039/C8AY02123F
Citation: Anal. Methods, 2018, Accepted Manuscript
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    Heavy metal ion discrimination based on distinct interaction between single-stranded DNA and methylene blue

    Z. Chen, L. Li and B. Liu, Anal. Methods, 2018, Accepted Manuscript , DOI: 10.1039/C8AY02123F

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