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Preparation and evaluation of molecularly imprinted membrane of teicoplanin

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Abstract

A molecularly imprinted membrane (MIM) with teicoplanin (TE) as a template and other related material membranes (organic nylon microporous membranes, polyvinylidene fluoride (PVDF) membranes, and polypropylene membranes) as supports were synthesized for the selective absorption of TE. These membranes can be used for pretreatment of biological samples and rapid determination of TE. Our results showed that PVDF MIM exhibited the best selectivity among the other three synthesized membranes and therefore, it was used in this study. The performance of PVDF MIM was examined, including surface structure, adsorption capacity, desorption capacity, selective adsorption capacity, and recovery rate; the precision, stability, repeatability, linearity and recovery rate of this method were investigated at the same time. Clean-up and enrichment of samples by TE MIM were reliable.

Graphical abstract: Preparation and evaluation of molecularly imprinted membrane of teicoplanin

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Publication details

The article was received on 20 Jul 2018, accepted on 25 Oct 2018 and first published on 26 Oct 2018


Article type: Paper
DOI: 10.1039/C8AY01623B
Citation: Anal. Methods, 2018, Advance Article
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    Preparation and evaluation of molecularly imprinted membrane of teicoplanin

    R. Yao, Z. Yu, M. Wu and H. Yu, Anal. Methods, 2018, Advance Article , DOI: 10.1039/C8AY01623B

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