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Efficient one-pot synthesis of carbon dots as fluorescence probe for selective and sensitive detection of rifampicin based on inner filter effect

Abstract

In this paper, carbon dots (CDs) emitting blue fluorescence was prepared using ammonium citrate and ammonium thiocyanate through a low-cost hydrothermal approach. The synthesized carbon dots with the maximum excitation and emission wavelength at 350 nm and 443 nm displayed excitation-independent photoluminescence behavior. The relative quantum yield of as-prepared carbon dots was measured to be 14%. Importantly, a novel method has been designed for rifampicin detection due to the fluorescence of carbon dots could be quenched significantly by rifampicin on the basis of inner filter effect quenching effect. Under the optimal experiment conditions, a satisfactory linear response relation was observed between the fluorescence quenching intensity of carbon dots and the concentration of rifampicin in the range of 0.43 to 49.0 mg L−1, and the detection limit for rifampicin was as low as 0.13 mg L−1. Therefore, the new method has been successfully established which is capable of quantification of rifampicin in real samples.

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Publication details

The article was received on 21 Jun 2018, accepted on 01 Aug 2018 and first published on 02 Aug 2018


Article type: Paper
DOI: 10.1039/C8AY01385C
Citation: Anal. Methods, 2018, Accepted Manuscript
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    Efficient one-pot synthesis of carbon dots as fluorescence probe for selective and sensitive detection of rifampicin based on inner filter effect

    Z. Han, Y. Long, S. Pan, H. Liu, J. Yang and X. Hu, Anal. Methods, 2018, Accepted Manuscript , DOI: 10.1039/C8AY01385C

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