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Reaction-based fluorescent probes for rapid detection of hydrogen sulfide in vivo

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Abstract

In this work, a series of novel fluorescent probes based on the fluorophores 3-benzothiazolyl-7-hydroxycoumarin/7-hydroxycoumarin were developed for detection of H2S. The probes exhibited excellent specific responses to H2S over other related competing species, including reactive sulfur, nitrogen and oxygen species. Moreover, the further successful imaging of the targetable fluorescent probe for sensing H2S in vivo was exciting and revealed that this targetable probe could serve as an efficient tool to study H2S-related chemical biology in physiological and pathological events.

Graphical abstract: Reaction-based fluorescent probes for rapid detection of hydrogen sulfide in vivo

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Publication details

The article was received on 24 May 2018, accepted on 24 Jul 2018 and first published on 01 Aug 2018


Article type: Paper
DOI: 10.1039/C8AY01176A
Citation: Anal. Methods, 2018, Advance Article
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    Reaction-based fluorescent probes for rapid detection of hydrogen sulfide in vivo

    X. Jin, X. Wu, P. Xie, S. Liu, J. Wu, T. Wang, H. Zhou, X. Leng and W. Chen, Anal. Methods, 2018, Advance Article , DOI: 10.1039/C8AY01176A

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