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Issue 21, 2018
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Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

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Abstract

Sensitive laser desorption/ionization obtained via a sublimation-coated 1,5-diaminonaphthalene (1,5-DAN) matrix allowed dual polarity MALDI-IMS analysis on the same pixel points across the jejunal mucosal region in rat small intestine which yielded high-spatial-resolution (10 μm) ion images of several lipid species correlated with the same histological features.

Graphical abstract: Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

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Supplementary files

Article information


Submitted
23 Mar 2018
Accepted
02 May 2018
First published
03 May 2018

This article is Open Access

Anal. Methods, 2018,10, 2428-2435
Article type
Communication

Dual polarity MALDI imaging mass spectrometry on the same pixel points reveals spatial lipid localizations at high-spatial resolutions in rat small intestine

I. Kaya, E. Jennische, S. Lange and P. Malmberg, Anal. Methods, 2018, 10, 2428
DOI: 10.1039/C8AY00645H

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